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Therefore, downregulation of XBP1 can effectively protect the kidneys from I/R-induced injury [113]

Glutathione binds to fat-soluble toxins, transforming them into water-soluble compounds that can be easily excreted through bile or urine

In mice, CHAC1/BOTCH promotes neuronal differentiation by inhibiting NOTCH1 and both its depletion and overproduction severely disrupt neurogenesis ( CHAC1/BOTCH in zebrafish leads to severe defects in brain, heart and myotome development, resulting in embryonic lethality, highlighting its conserved and essential role (Yadav et al., 2019)

I consider naturally as can I get from diet